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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZDHHC14 All Species: 27.27
Human Site: S478 Identified Species: 50
UniProt: Q8IZN3 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IZN3 NP_078906.2 488 53388 S478 Q D S L H E D S V R G L V K L
Chimpanzee Pan troglodytes XP_001143896 464 50937 S454 Q D S L H E D S V R G L V K L
Rhesus Macaque Macaca mulatta XP_001093039 488 53343 S478 Q D S L H E D S V R G L V K L
Dog Lupus familis XP_854971 420 45636 V411 D S L H E D S V R G L V K L S
Cat Felis silvestris
Mouse Mus musculus Q8BQQ1 489 53640 S479 Q D S L H E D S V R G L V K L
Rat Rattus norvegicus Q2TGJ1 386 41641 P377 E P A C G A K P D A S M V G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232232 491 53709 S481 Q D S L H E D S V R G L V K L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001038652 513 56361 S503 Q D S L H E D S V R G L V K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001137936 693 74989 C674 M G N N S Q S C L V K S G K P
Honey Bee Apis mellifera XP_395517 664 74472 S598 D E I A P L P S R Q S I V V S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796142 543 59493 S533 H D A F Q T P S Q C G I L K L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SB58 407 46728 S398 T D V R E S R S Y A T A K D G
Baker's Yeast Sacchar. cerevisiae Q06551 359 41080 A350 R F M D L S P A H S F E K I Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95 99.8 80.9 N.A. 94.8 50.4 N.A. N.A. 89.6 N.A. 66.6 N.A. 37.2 41.8 N.A. 41.9
Protein Similarity: 100 95 100 82.7 N.A. 97.7 58.6 N.A. N.A. 93.8 N.A. 76.2 N.A. 50.2 51.6 N.A. 57
P-Site Identity: 100 100 100 0 N.A. 100 6.6 N.A. N.A. 100 N.A. 100 N.A. 6.6 13.3 N.A. 33.3
P-Site Similarity: 100 100 100 13.3 N.A. 100 26.6 N.A. N.A. 100 N.A. 100 N.A. 26.6 33.3 N.A. 53.3
Percent
Protein Identity: N.A. N.A. N.A. 28.6 22.5 N.A.
Protein Similarity: N.A. N.A. N.A. 45.7 38.1 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 16 8 0 8 0 8 0 16 0 8 0 0 0 % A
% Cys: 0 0 0 8 0 0 0 8 0 8 0 0 0 0 0 % C
% Asp: 16 62 0 8 0 8 47 0 8 0 0 0 0 8 0 % D
% Glu: 8 8 0 0 16 47 0 0 0 0 0 8 0 0 0 % E
% Phe: 0 8 0 8 0 0 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 8 0 0 8 0 0 0 0 8 54 0 8 8 16 % G
% His: 8 0 0 8 47 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 16 0 8 0 % I
% Lys: 0 0 0 0 0 0 8 0 0 0 8 0 24 62 0 % K
% Leu: 0 0 8 47 8 8 0 0 8 0 8 47 8 8 54 % L
% Met: 8 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 0 8 8 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 0 8 0 24 8 0 0 0 0 0 0 8 % P
% Gln: 47 0 0 0 8 8 0 0 8 8 0 0 0 0 8 % Q
% Arg: 8 0 0 8 0 0 8 0 16 47 0 0 0 0 0 % R
% Ser: 0 8 47 0 8 16 16 70 0 8 16 8 0 0 16 % S
% Thr: 8 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % T
% Val: 0 0 8 0 0 0 0 8 47 8 0 8 62 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _